Beth B. DuPree, Michael J. Papez, Elaina Pirruccello, Audrey Hassenﬂug; Indian Journal of Surgery, Nov. 26, 2021; Association of Surgeons of India 2021
This paper reports on the intraoperative use of Optical Coherence Tomography (OCT) in 3 patients with DCIS. In all 3 cases, additional lesions identiﬁed by OCT during surgery were also noted in histopathology reports 3 to 5 days post-surgery, suggesting that intraoperative use of OCT is a valuable tool for margin determination in real-time.
Hank Schmidt, Courtney Connolly, Shabnam Jaﬀer, Twisha Oza, Christina R Weltz, Elisa R Port, Adriana Corben; The Breast Journal, Oct. 14, 2019
In this pilot study, evaluation of wide-ﬁeld Optical Coherence Tomography demonstrated concordance with histology at tissue margins, supporting its potential for use as a real-time adjunct intraoperative imaging tool for margin assessment in surgically excised breast tissue.
Richard Ha, MD; Lauren C. Friedlander, MD; Hanina Hibshoosh, MD; Christine Hendon, PhD; Sheldon Feldman, MD; Soojin Ahn, MD; Hank Schmidt, MD, PhD; Margaret K. Akens, PhD; MaryAnn Fitzmaurice, MD, PhD; Brian C. Wilson, PhD; Victoria L. Mango, MD; Academic Radiology, Nov. 22, 2017
Study results display the potential for Optical Coherence Tomography (OTC) as a real-time intraoperative tool for post-lumpectomy specimen margin assessment. This study revealed a relatively short training time and showed that readers from diﬀerent medical specialties were able to distinguish suspicious from non-suspicious OCT imaging ﬁndings in ex vivo breast tissue conﬁrmed by histology.
Lee Wilke, Adriana Corben, Elisa Port, Christina Weltz2, J. Jamie Alberty-Oller, Kaelin Grant, Mitch Piel, Hank Schmidt; ASBrS, Oﬃcial Proceedings, Volume XXI, PAGE 187, 2020 Virtual Scientiﬁc Session
This abstract presents the eﬀectiveness of lumpectomy specimen stabilization with a compression bag using Perimeter’s OTIS™ Optical Coherence Tomography (OTC) device. The use of compression to improve lumpectomy specimen imaging did not compromise specimen integrity for pathology and showed no statistical diﬀerence in re-excision rates. The OTIS™ OCT device seamlessly integrated into the intraoperative workﬂow for breast specimen imaging.