Cancer surgeons have long recognized the challenge of achieving clean margins while preserving healthy tissue during surgery. Traditional intraoperative imaging does not have the resolution to see microscopic features associated with cellular-level disease, like DCIS.2 And it’s several days or weeks before pathology reports on margin status are available. If pathology shows positive margins, patients must typically return for another procedure due to cancer left behind.
Perimeter’s OCT technology delivers the clinical edge healthcare providers need to improve patient satisfaction and offer the most advanced care.


Despite advances in imaging and pathology, positive margins remain one of the most persistent challenges in breast-conserving surgery.
Traditional imaging like X-ray, Ultrasound and CT are too low in resolution to visualize microscopic disease, resulting in cancer being missed at the margins of excised tissue or “positive margins.”
Claire was designed to change that.
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Optical Coherence Tomography (OCT) technology, developed out of MIT in 1991, has been successfully used in ophthalmology, cardiology, GI, and dermatology for decades. Clinicians rely on OCT’s ultra-high-resolution imaging power to view microscopic subsurface tissues to help them make more informed clinical decisions.
Now, Perimeter is revolutionizing intraoperative margin visualization with its patented wide-field OCT technology that stitches OCT images together, creating the ability to scan larger tissue specimens and correlate microstructures to key features seen in post-op Pathology when determining margin status.