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Perimeter S-Series Product Information

S-Series Brochure

Perimeter S-Series OCT (Optical Coherence Tomography) is a pioneering medical imaging system that provides cross-sectional, real-time margin visualization of excised tissue specimens in the operating room.

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What is OCT? Information Sheet

OCT is a non-invasive optical imaging technique that produces images of subsurface tissue structures. Analogous to ultrasound, it uses light instead of sound, resulting in 10x higher resolution. This brochure provides more information on the benefits of OCT and how it works.

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Clinical Resources

Potential Utility of Adjunct Imaging with Wide‑Field Optical Coherence Tomography for Gross and Microscopic Evaluation of Breast Specimens in Real‑Time in the Operating Suite

This paper reports on the intraoperative use of Optical Coherence Tomography (OCT) in 3 patients with DCIS. In all 3 cases, additional lesions identified by OCT during surgery were also noted in histopathology reports 3 to 5 days post-surgery, suggesting that intraoperative use of OCT is a valuable tool for margin determination in real-time. (DuPree, et al, 2021)

Updated: August 6, 2021

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Evaluation of surgically excised breast tissue microstructure using wide-field Optical Coherence Tomography

In this pilot study, evaluation of wide-field Optical Coherence Tomography demonstrated concordance with histology at tissue margins, supporting its potential for use as a real-time adjunct intraoperative imaging tool for margin assessment in surgically excised breast tissue. (Schmidt, et al, 2019)

Updated: October 14, 2019

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Optical Coherence Tomography: A Novel Imaging Method for Post-lumpectomy Breast Margin Assessment—A Multi-reader Study

Study results display the potential for Optical Coherence Tomography (OTC) as a real-time intraoperative tool for post-lumpectomy specimen margin assessment. This study revealed a relatively short training time and showed that readers from different medical specialties were able to distinguish suspicious from non-suspicious OCT imaging findings in ex vivo breast tissue confirmed by histology. (Ha, et al, 2017)

Updated: March 1, 2018

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Feasibility Study of the Intra-operative Use of the OTIS™, Wide Field Optical Coherence Tomography (WF-OCT) in Surgically Excised Partial-mastectomy Breast Tissue

This abstract presents the effectiveness of lumpectomy specimen stabilization with a compression bag using Perimeter’s OTIS™ Optical Coherence Tomography (OTC) device. The use of compression to improve lumpectomy specimen imaging did not compromise specimen integrity for pathology and showed no statistical difference in re-excision rates. The OTIS™ OCT device seamlessly integrated into the intraoperative workflow for breast specimen imaging. (PAGE 187, Wilke, et al, 2020)

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Is OCT the Next Game Changer in Margin Visualization?

Presenting multiple patient cases using a new FDA-cleared intraoperative specimen imaging technology for real-time visualization of excised tissue and shaved margins with surgeons from three prestigious institutions involved in Perimeter’s clinical trials. This webinar provides a deeper dive on Optical Coherence Tomography (OCT) – an established, ultra-high-resolution technology used in cardiology, dermatology, and ophthalmology – and correlates OCT images to histopathology.

Presented by Nina Tamirisa, MD, Maryam Elmi, MD, and Stacey Carter, MD, FACS

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Next Generation in Surgical Specimen Imaging with Future AI Enhancements

Learn more about advancements in intraoperative specimen imaging. Optical Coherence Tomography (OCT), a high resolution imaging modality commonly used in ophthalmology and cardiology, is ideally suited to visualizing margins during a surgical procedure. This webinar also includes insights into how Artificial Intelligence is moving towards the OR and Specimen Imaging.

Presented by Dr. Hank Schmidt, Dr. Beth DuPree, and Dr. Alastair Thompson

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General Resources

Mary's Story

Mary Leas discusses her breast cancer diagnosis and involvement in a clinical trial using Perimeter’s technology.

Suzanne's Story

Hear Suzanne talk about the fear she experienced with her cancer diagnosis and being called back for a second surgery.

Jenn's Story

Jenn describes how her battle with cancer affected her outlook on life.

Jessie's Story

Jessie Henson discusses her breast cancer diagnosis and involvement in a clinical trial using Perimeter’s technology.

Perimeter Does

Traditional intraoperative imaging modalities do not deliver the resolution to visualize microscopic features associated with cellular-level disease. Perimeter is looking to become the answer to intraoperative margin visualization with its OCT technology.

Perimeter S-Series OCT Introduction

Our flagship product, Perimeter S-Series OCT (Optical Coherence Tomography) is a pioneering medical imaging system that provides cross-sectional, real-time margin visualization of excised tissue specimens in the operating room (OR).

Corporate Introduction

Jeremy Sobotta, CEO, introduces Perimeter Medical Imaging AI, a medical technology company driven to transform cancer surgery by developing advanced imaging systems that improve the standard of care, provide better long-term outcomes for patients and reduce healthcare costs.

2021 Year in Review

From FDA clearance of Perimeter Medical Imaging AI's S-Series OCT device to our first commercial installation and the launch of our pivotal trial, 2021 was a year full of milestones. With this momentum, we’ll continue our mission to transform cancer surgery and improve patients’ lives in 2022.

Perimeter Overview

Perimeter Medical Imaging AI provides the medical community with innovative imaging tools needed to build confidence in the operating room.

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